Our Strength

WATSON NOKE’s expertise is in the synthesis of complicated heterocyclic compounds. Our original development focused on the five series of chemicals below,

  • Ferrocen derivatives
  • Triphenylbismuth and Tris(4-ethoxyphenyl)bismuthine
  • Fluoro series
  • Fumarate series
  • Some other heterocyclic compounds

Later, we turned to two more classes according to customers’ requirement,

  • Furan series
  • Complicated amino acids such as some protected ones

After that, more are on schedule even including some active pharmaceutical ingredients, but all kinds of intermediates are still our priorities considering the documents requirement of APIs.

We do not specialize in chemicals of some certain particular applications, but consider them from aspect of synthesis possibility. But you still find “Chemicals by application” in our website, because this may help you find their required products quickly and easily.

Expertise

Acetylation
Acylation
Alkylation
Amidation
Ammonolysis
Bromination
Chlorination
Chloromethylation
Chlorosulfonation
Condensation
Cyclization
Dehalogenation
Dehydrohalogenation
Elimination
Esterification
Etherification
Formylation
Friedel-Carfts acylation
Fries rearrangement
Gabriel synthesis
Grignard reaction
Halide exchange
Hofmann degradation
Hydrogenation(catalytical)
Methylation
Newman-Kwart rearrangement
Nitration
Nitrosation
Oxidation
Phase transfer reaction
Reduction(Catalytical, metal hydrides)
Ring Fusion
Rosenmund reduction
Sandmeyer reaction
Saponification
Schotten-Baumann reaction
Substitution
Sulfation
Sulfonation
Transesterification
Vilsmeier reaction
Williamson ether synthesis